[] ⒉免疫功能缺陷病人的获得性弓形虫病先天性和获得性免疫功能缺陷患者感染弓形虫的危险性极大，特别是潜在性感染的复发。在这种情况下获得性弓形虫病的淋巴结病变可不明显，可能出现广泛播散和迅速发生的致命性感染，表现为高热、肺炎、皮疹、肝脾肿大、心肌炎、肌炎、丸炎。甚至引起脑弓形虫病。典型的脑弓形虫病以亚急性方式起病、有头痛、偏瘫、癫痫发作、视力障碍、神志不清，甚至昏迷，发热与脑膜刺激征较少见。脑脊液检查可见少数红细胞，单核细胞轻度增多，蛋白稍增高，糖可*正常，偶有降低。CT检查显示脑炎改变，也可呈现单个或多个对比度增强的占位性病灶，直径小于cm，多发生于基底神经节。强化后呈环形或结节状增强。[] 除上述提到的几种病以外：.如果怀孕头个月发生先天性感染，大约%胎儿可能有严重的损害，出现流产、死胎或新生儿疾病，或者出生后有眼、脑或肝脏的病变或畸形，如视网膜脉络膜炎、白内障、脑内钙化、脑积水、小头畸形、智力障碍、黄疸和肝脾肿大。怀孕末个月发生的感染，严重者不到%。[] [] .相对其他来说，免疫能力低的孕妇和儿童，将zui可能受到这种寄生虫影响。
2. Acquired toxoplasmosis in immunocompromised patients Patients with congenital and acquired immunodeficiency have a high risk of infection with Toxoplasma gondii, especially the recurrence of underlying infections. In this case, the acquired lymph node lesions of toxoplasmosis may not be obvious, and there may be widespread dissemination and rapid fatal infections, manifested as high fever, pneumonia, rash, hepatosplenomegaly, myocarditis, myositis, and pill inflammation. It even causes cerebral toxoplasmosis. Typical toxoplasmosis occurs in subacute form, with headache, hemiplegia, seizures, visual disturbances, confusion, and even coma. Fever and meningeal irritation are less common. Cerebrospinal fluid examination showed a few red blood cells, a slight increase in monocytes, a slight increase in protein, sugar can be compley normal, occasionally reduced. CT examination revealed changes in encephalitis, and may also present with single or multiple contrast-enhancing lesions occupying less than 1 cm in diameter and occurring mostly in the basal ganglia. After strengthening, it has a circular or nodular enhancement. [] In addition to the above-mentioned several diseases: If fetal congenital infection occurs in the first month of pregnancy, approximay % of fetuses may have severe damage, have miscarriage, stillbirth or neonatal disease, or have eyes, brain or liver after birth Lesions or malformations such as retinal choroiditis, cataracts, intracerebral calcification, hydrocephalus, microcephaly, mental retardation, jaundice, and hepatosplenomegaly. Less than 90% of serious infections occur during the last months of pregnancy. [] [] . Relatively low-immunity pregnant women and children are most likely to be affected by this parasite.

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