前瞻性研究表明先天性感染的发生率和严重性与孕妇受染时间的早晚有关：妊娠早期感染弓形虫病的孕妇，如不接受治疗则可引起%～%先天性感染而导致自然流产、死胎、早产和新生儿严重感染;妊娠中期与后期感染的孕妇分别可引起%～%(其中～%可无症状)和～%(内%～%可无症状)的胎儿感染。受染孕妇如能接受治疗，则可使先天性感染的发生率降低%左右。先天性弓形虫病的临床表现不一。多数婴儿出生时可无症状，其中部分于出生后数月或数年发生视网膜脉络膜炎、斜视、失明、癫痫、精神运动或智力迟钝等。出生时即有症状者梋下列不同组合的临床表现：视网膜脉络膜炎;脑积水或小并没有畸形或无脑儿、颅内钙化，伴脊柱裂、脑脊膜膨出、兔唇腭裂;肾上腺缺如、双多囊肾;联体畸胎等;抽搐、精神运动障碍;淋巴结肿大、肝脾肿大、发热、黄疸、皮疹等。[] 后天获得性弓形虫病获得性弓形虫病可因虫体侵袭部位和机体反应性而呈现不同的临床表现。因而无特异症状，须与有关疾病鉴别。患者多数与职业、生活方式、饮食习惯有一定关系。淋巴结肿大是获得性弓形虫病zui常见的临床类型，多见于颌下和颈后淋巴结。其次弓形虫常累及脑、眼部，引起中枢神经系统异常表现，在免疫功能低下者，常表现为脑炎、脑膜脑炎、癫痫和精神异常。
Prospective studies have shown that the incidence and severity of congenital infections are related to the timing of maternal infection: Pregnant women infected with toxoplasmosis in the early stages of pregnancy may cause % to % congenital infections resulting in spontaneous abortions and stillbirths if they are not treated. , Premature birth and serious neonatal infections; pregnant women with mid- and late-term infections can cause fetal infections with %-% (of which ~% can be asymptomatic) and ~% (internal %-% can be asymptomatic). If infected pregnant women can receive treatment, the incidence of congenital infections can be reduced by about %. The clinical manifestations of congenital toxoplasmosis vary. Most babies are asymptomatic at birth, and some of them develop retinochoroiditis, strabismus, blindness, epilepsy, mental activity, or mental retardation several months or years after birth. The clinical manifestations of those with symptoms at birth are the following: retinochoroiditis; no or abnormal brain hydrocephalus, or intracranial calcification, with spina bifida, meningocele, or cleft lip; Such as, double polycystic kidney; conjoined teratogenic; convulsions, mental movement disorders; lymphadenopathy, hepatosplenomegaly, fever, jaundice, rash and so on. [] Acquired toxoplasmosis acquired toxoplasmosis can present with different clinical manifestations due to the site of attack and body reactivity. Therefore, no specific symptoms must be identified with the relevant diseases. Most patients have a certain relationship with occupation, lifestyle, and eating habits. Lymph node enlargement is the most common clinical form of acquired toxoplasmosis and is most commonly found in submandibular and cervical lymph nodes. Second, Toxoplasma gondii often involving the brain, eyes, causing abnormal performance of the central nervous system, in immunocompromised persons, often manifested as encephalitis, meningoencephalitis, epilepsy and mental disorders.

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