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【公司名称】 广州健仑生物科技有限公司
【市场部】 杨永汉
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【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室
在保罗-李博士看来,“胰岛素敏感性提升与棕色脂肪的增加同步,在未来,这或许能开启新的治疗方法,阻碍糖分代谢。另一方面,由于当代社会供热上升,人们在轻度寒冷的条件下暴露的时间减短,这可能损害棕色脂肪的功能,造成肥胖、代谢紊乱。”
“研究显示,过去几十年中在英国、美国家庭卧室、餐厅、客厅的温度从19摄氏度攀升至22摄氏度,这也将导致棕色脂肪生成减弱。因此,除了不健康的饮食、缺乏运动之外,在较高温度下暴露时间增长,也可能是导致肥胖的因素之一。”
蝾螈成功再生身体部位的秘密正在被揭开,伦敦大学学院的研究人员为了将其应用于人类。首先,研究人员发现‘ERK通路’必须不断地活动为蝾螈细胞进行重新编程,从而能够有助于不同身体部位的再生。
该研究小组发现在蝾螈和哺乳动物之间这一通路的主要差异,有助于我们理解为什么人类不能再生四肢,并揭示人类细胞的再生怎样改善。文章发表在《Stem Cell Reports 》期刊上。
研究证明ERK通路在哺乳动物细胞中并不十分活跃,但是当强迫其不断活动时,使得细胞更多可能性为重编程和再生。这可能有助于研究人员更好了解疾病并设计新疗法。
这项研究的*研究员,Max Yun 博士(伦敦大学学院结构与分子生物学)说:“虽然人类只有有限的再生能力,其他生物,如蝾螈,能够再生复杂结构的所有组成成分,包括它们的心脏、眼睛、脊髓、尾巴等部分,而且它们是*的成体脊椎动物能够再生出完整四肢的。”
In Dr. Paul Lee's view, "Insulin sensitivity increases in tandem with the increase in brown fat, which in the future may open new avenues of treatment that will hinder sugar metabolism." On the other hand, people are being light due to rising heat in today's society Degrees of exposure to cold conditions are reduced, which may impair the function of brown fat, causing obesity and metabolic disorders. "
Studies have shown that in the United Kingdom in the past decades, the temperature in American family bedrooms, dining rooms and living rooms has risen from 19 degrees Celsius to 22 degrees Celsius, which will also lead to a decrease in brown fat production, so in addition to an unhealthy diet and lack of exercise, Exposure to increased temperatures at higher temperatures may also be one of the factors contributing to obesity. "
The secrets of successfully regenerating the body parts of the salamander are being uncovered, and researchers at the University College London apply it to humans. First, the researchers found that the 'ERK pathway' must be constantly reprogrammed for salamander cells to help regenerate different parts of the body.
The team found that the major differences in this pathway between salamander and mammals helped us to understand why humans can not regenerate their limbs and reveal how human cell regeneration can improve. Article published in "Stem Cell Reports" journal.
Studies have shown that the ERK pathway is not very active in mammalian cells, but when forced to continue its activity, the cells are more likely to be reprogrammed and regenerated. This may help researchers better understand the disease and design new therapies.
Dr. Max Yun, chief researcher of the study, Structural and Molecular Biology, University College London, said: "While humans have only limited ability to regenerate, other organisms, such as salamanders, are able to regenerate all the components of a complex structure, including their Heart, eyes, spinal cord, tail and other parts, and they are the only adult vertebrates capable of regenerating intact limbs. "